January 1970


find related articles. powered by google. ePrairie University of Illinois at Chicago Bioinformatics Program a 'Well-Kept Secret'

"The University of Illinois at Chicago (UIC) is currently the only learning institution in the state that possesses an accredited bioinformatics program. UIC offers 12 credits in bioinformatics through a program called BiTmaP.

"It's a well-kept secret -- this program -- because the tuition is free," BiTmaP program director Ann Reed told ePrairie.

BiTmaP is a free training program sponsored by the U.S. Department of Labor through a $3 million grant awarded to the Chicago Technology Park. The program was created with the intent to bridge the growing gap between unemployed or underemployed IT professionals and the booming life sciences community."

find related articles. powered by google. eMaxHealth Finding Gives Boost To Bioinformatics Use in Fighting Disease

"The use of computers to advance human disease research – known as bioinformatics - has received a major boost from researchers at the La Jolla Institute for Allergy & Immunology (LIAI), who have used it to successfully predict immune response to one of the most complex viruses known to man – the vaccinia virus, which is used in the smallpox vaccine. Immune responses, which are essentially how the body fights a disease-causing agent, are a crucial element of vaccine development."

"While bioinformatics – which uses computer databases, algorithms and statistical techniques to analyze biological information - is already in use as a predictor of immune response, the LIAI research team's findings were significant because they demonstrated an extremely high rate of prediction accuracy (95 percent) in a very complex pathogen – the vaccinia virus."

find related articles. powered by google. Nature Peer Review Trial and Debate

"Nature is undertaking a trial of a particular type of open peer review. In this trial, authors whose submissions to Nature are sent for peer review will also be offered the opportunity to participate in an open peer review process (see below for explanation). The trial is optional for authors; it will continue in parallel with Nature's usual procedures, and does not affect the likelihood of eventual publication of the submitted work. At the same time as the trial, Nature is running a web debate on peer review, to which we welcome comments from readers."

"The web debate contains a range of perspectives about peer review from those who believe it is working well, to those who prefer other options. What is the value of peer review, and how does it ensure quality? What are the ethical concerns? Are there viable alternatives, either technical or in terms of management of the process? And above all, what is the scientists' experience of the process, either as authors or as reviewers themselves? Nature's web debate provides a lively range of views, updated weekly."

redux [05.02.06]
find related articles. powered by google. The New York Times For Science's Gatekeepers, a Credibility Gap
[requires 'free' registration]

"Recent disclosures of fraudulent or flawed studies in medical and scientific journals have called into question as never before the merits of their peer-review system."

"Virtually every major scientific and medical journal has been humbled recently by publishing findings that are later discredited. The flurry of episodes has led many people to ask why authors, editors and independent expert reviewers all failed to detect the problems before publication."

redux [03.02.06]
find related articles. powered by google. The Scientist Is Peer Review Broken?
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"Despite a lack of evidence that peer review works, most scientists (by nature a skeptical lot) appear to believe in peer review. It's something that's held "absolutely sacred" in a field where people rarely accept anything with "blind faith," says Richard Smith, former editor of the BMJ and now CEO of UnitedHealth Europe and board member of PLoS. "It's very unscientific, really.

Indeed, an abundance of data from a range of journals suggests peer review does little to improve papers. "

redux [08.15.05]
find related articles. powered by google. The Boston Globe Flaws are found in validating medical studies

"Now, after a study that sent reverberations through the medical profession by finding that almost one-third of top research articles have been either contradicted or seriously questioned, some specialists are calling for radical changes in the system."

In advance of a world congress on peer review next month in Chicago, these specialists are suggesting that reviewers drop their anonymity and allow comments to be published."

""It would be lovely to start anew and to set up a trial of peer review against no peer review," Rennie said. "But no journal is willing to risk it.""

Cigarette smoking has been identified as a strong risk factor for erectile dysfunction (ED). The authors of this study have attempted to identify whether smoking cessation reverses ED in men who previously smoked cigarettes.

They studied men with ED who entered a nicotine replacement program for smoking termination. The men studied had no risk factors for ED other than smoking. Degree of ED was categorized by the erectile function domain (EFD) score of the International Index of Erectile Function. Patients completed the IIEF on entry into the nicotine replacement program and one year later after cessation of smoking or after one year of continued smoking. There were 118 men who stopped smoking after the nicotine replacement program and 163 men who continued to smoke...

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A Harrow Weald man who ran one of Europe's largest counterfeit Viagra factories had his GBP 1.2 million confiscation order upheld by top judges yesterday (Friday).

Allen Valentine was jailed for five-and-a-half-years after admitting conspiracy to supply class C drugs between January 1 2001 and April 21 2004 as well as two charges involving breaches of the Trade Marks Act and Medicines Act.

He was handed the sentence in October 2004 at Harrow Crown Court and was also hit with the GBP 1,216,940 confiscation order, which he challenged unsuccessfully.

Valentine, 46, of Kynaston Wood, Harrow, was prosecuted after police raided his factory in April 2004.

His business, in Wembley, with a warehouse in Watford, could produce 500,000 tablets a day, the prosecution claimed...

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